COURSE OVERVIEW

 

This practical and highly-interactive course includes real-life case studies where participants will be engaged in a series of interactive small groups and class workshops. 

This course is designed to provide participants with a detailed and up-to-date overview of Antibody Engineering, Phage display and Immune Repertoire Analysis. It covers the structure and function of antibodies including the importance of antibodies in food safety and diagnostics; the basics of antibody engineering and the tools and technologies for antibody engineering; the antibody-target interactions and challenges in antibody engineering; the phage display, phage library construction and proper selection of high-affinity antibodies; and the pathogen-specific antibodies, foodborne contaminants and pesticide residues and toxins. 

 

During this interactive course, participants will learn the common issues in library design, panning, non-specific binding and background noise; the basics of B-cell and T-cell repertoires and the role of immune repertoires in pathogen detection; the immune repertoire analysis, agriculture and food safety and data analysis and interpretation; the emerging trends in immune repertoire analysis including humanization and affinity maturation; the antibody-based diagnostic kits and rapid testing for foodborne pathogens; the therapeutic antibodies in agriculture, antibody conjugates and regulatory and ethical considerations; the innovations in phage display technology; and the role in combating antimicrobial resistance and synthetic and computational approaches.